Research in extracellular vesicles has skyrocketed since its discovery 30 years ago due to its potential medical applications in treating diseases such as cancer, because of its essential role in remote communication between cells. This is one of the current lines of research of Dr. Antonio Marcilla, Professor at the Department of Cell Biology and Parasitology at the University of Valencia, and member of the GEIVEX Managing Board (Spanish Group of Innovation and Research in Extracellular Vesicles). Marcilla completed his training as a researcher at the course on extracellular vesicles, held at the premises of Menéndez Pelayo International University in Valencia. Marcilla talks about these spheres that «some even describe as if they were soap bubbles».
How would you define extracellular vesicles?
Why do they suppose a medical revolution?
Do all extracellular vesicles carry information?
How can we generate vesicles that transport certain information?
Does the nanoscopical scale represent a challenge for your research?
Is there any chance of using vesicles from other organisms to end human diseases?
And also from worms?
What are the purification techniques of extracellular vesicles about?
Could the cell degradation that comes with aging be addressed and corrected with extracellular vesicles?
In short, could we say that all diseases based on cell failure would have a possible solution by treating them with extracellular vesicles?
What application might vesicles have in the production of vaccines?
Teresa Coll. Student of Journalism at the University of Valencia.
«The extracellular vesicles are supposed to communicate cells that can be found over long distances»
«Vesicles that are naturally-occurring or produced by living organisms can be manipulated to incorporate the desired material therein»
«Vesicles could be designed for a given treatment from bacteria»
«Any disease in which there is communication between a pathogenic cell and a healthy cell is sensitive of being locked by means of extracellular vesicles»
«In the case of bacterial diseases, it has already been seen that some may be preventable by previously managing vesicles from these pathogen organisms»