An epidemic like the one we have unfortunately experienced can bring out people's worst fears. Cinema and literature have successfully used fear to write scripts in which an epidemic is the heart of the story or the underlying excuse.
In the West, our idea of animated cinema is very much influenced by the work of Walt Disney. In Japan, the animated film tradition (anime) is very different. Complicated plots that are often not clearly targeted at a child or adult audience and ambiguous characters. Eastern animated cinema can even dare to make a film speculating on the philosophy of science.